RichR: Enrichment for Diseases in a Set of Genes

It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) <doi:10.18547/gcb.2016.vol2.iss1.e33>, DisGeNET, Pinero (2016) <doi:10.1093/nar/gkw943> Berto2016, Berto (2016) <doi:10.3389/fgene.2016.00031> and PsyGeNET, Sacristan (2015) <doi:10.1093/bioinformatics/btv301>). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.

Version: 1.0.0
Depends: R (≥ 3.1)
Imports: plyr, reshape2, magrittr, stats, metap
Published: 2019-02-22
Author: Deisy Morselli Gysi and Katja Nowick
Maintainer: Deisy Morselli Gysi <deisy at bioinf.uni-leipzig.de>
License: GPL-2
NeedsCompilation: no
CRAN checks: RichR results

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Reference manual: RichR.pdf
Package source: RichR_1.0.0.tar.gz
Windows binaries: r-devel: RichR_1.0.0.zip, r-release: RichR_1.0.0.zip, r-oldrel: RichR_1.0.0.zip
OS X binaries: r-release: RichR_1.0.0.tgz, r-oldrel: RichR_1.0.0.tgz

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